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Plinest Polynucleotide (DNA)

Plinest in skin biorevitalization procedures is successfully used by cosmetologists all over the world to restore the health of the skin, increase turgor and achieve a significant rejuvenating effect. The principle of action of the innovative Plinest repair system is based on the activation of the skin’s own cellular resources. 

Plinest is an injectable that consists of highly purified natural origin long chain polynucleotide. It combats the effects of aging by helping fibroblasts produce the needed collagen and non-collagenic molecules to smoothen and revitalize the areas of the face or body that show signs of aging.

Benefits of Plinest

Around 140 patients were tested and given Plinest. Results show that 91% have improved skin and through minimized wrinkles. In another separate study, 14 patients showed increased skin elasticity and hydration.

  • Increases collagen production
  • Corrects superficial wrinkles
  • Boosts hyaluronic acid
  • Increases skin turgidity and hydration
  • Oxygenates skin

Revitalizes skin



In aged skin, fibroblast attachment is impaired due to progressive ECM degradation, resulting in fibroblast size reduction, decreased elongation, and collapsed morphology.

It is a natural DNA fractions, they are able to activate the physiological cellular regeneration through a direct stimulation of fibroblast cells. The result is an increase of fibroblasts regeneration, and an increase of production of collagen and extracellular matrix protein ECM, including hyaluronic acid.

You will start to notice skin improvements within three to five sessions and will continue for the next months because of the activated fibroblast. The effects will last depending on the patient’s skin condition and lifestyle.